Buy Eszopiclone (Lunesta) 2 mg, 3 mg tablets

Buy Eszopiclone (Lunesta) tablets online

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Indications and usage:

Lunesta is indicated for the treatment of insomnia. Eszopiclone has been shown to decrease sleep latency and improve sleep maintenance.

Dosage and administration:

Use the lowest dose effective for the patient.

Recommended initial dose is 1 mg, immediately before bedtime, withat least 7-8 hours remaining before the planned time of awakening. May increase dose if clinically indicated, to a maximum of 3 mg.

Geriatric or debilitated patients: dose should not exceed 2 mg.

Patients with severe hepatic impairment, or taking potent CYP3A4 inhibitors: dose should not exceed 2 mg.

Do not take with or immediately after a meal.

Dosage forms and strengths:

Lunesta (Eszopiclone) tablets: 1 mg, 2 mg, and 3 mg.

Contraindications:

Patients who have experienced complex sleep behaviors after taking this medication.

Known hypersensitivity to eszopiclone.

Warnings and precautions:

CNS depressant effects: impaired alertness and motor coordination, including risk of morning impairment. Risk increases with dose and use with other CNS depressants and alcohol. Caution patients taking 3 mg dose against driving and against activities requiring complete mental alertness during the morning after use.

Evaluate for comorbid diagnoses: reevaluate if insomnia persists after 7 to 10 days of use.

Severe anaphylactic/anaphylactoid reactions (angioedema and anaphylaxis have been reported): do not rechallenge if such reactionsoccur.

Abnormal thinking and behavioral changes: changes including decreased inhibition, bizarre behavior, agitation and depersonalization have been reported. Immediately evaluate any new onset of behavioral changes.

Worsening of depression or suicidal thinking may occur: prescribe the least number of tablets feasible to avoid intentional overdose.

Withdrawal effects: symptoms may occur with rapid dose reduction or discontinuation.

Elderly patients: use lower dose due to impaired motor, cognitive performance and increased sensitivity.

Patients with hepatic impairment, impaired respiratory function, impaired drug metabolism or hemodynamic responses: use with caution.

Overdosage:

In clinical trials with eszopiclone, one case of overdose with up to 36 mg of eszopiclone was reported in which the subject fully recovered. Since commercial marketing began, spontaneous cases of eszopiclone overdoses up to 270 mg (90 times the maximum recommended dose of eszopiclone) have been reported, in which patients have recovered. Fatalities related to Lunesta overdoses were reported only in combination with other CNS drugs or alcohol.

Side effects, adverse reactions:

Most commonly observed eszopiclone adverse reactions (incidence >= 2%) were unpleasant taste, headache, somnolence, respiratory infection, dizziness, dry mouth, rash, anxiety, hallucinations, and viral infections.

To report suspected side effects of Lunesta (Eszopiclone) tablets, contact Sunovion Pharmaceuticals Inc. or your local FDA.

Drug abuse and dependence:

Eszopiclone is a controlled substance by local laws in some countries (for example, Schedule IV in the United States and Canada). Other substances under the same classification are benzodiazepines and the nonbenzodiazepine hypnotics Zaleplon and Zolpidem (Belbien).

Drug interactions:

CNS depressants: additive CNS-depressant effects with combination use. Use with ethanol causes additive psychomotor impairment.

Rifampicin: combination use may decrease exposure and effects of eszopiclone.

Ketoconazole: combination use increases exposure and effect of Lunesta. Dose reduction of this medication is needed.

Use in specific populations:

Pregnancy

Available pharmacovigilance data with this medicine use in pregnant women are insufficient to identify a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes.

Lactation

There are no data on the presence of eszopiclone in either human or animal milk, the effects on the breastfed infant, or the effects on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Lunesta and any potential adverse effects on the breastfed infant from this drug or from the underlying maternal condition.

Pediatric use

Safety and effectiveness not established. Dizziness, dysgeusia, hallucinations, suicidal ideation reported.

Geriatric use

The overall pattern of adverse events for elderly subjects (median age = 71 years) in 2-week studies with nighttime dosing of 2 mg eszopiclone was not different from that seen in younger adults. Lunesta 2 mg exhibited significant reduction in sleep latency and improvement in sleep maintenance in the elderly population.

Hepatic impairment

No dose adjustment is necessary for patients with mild-to-moderate hepatic impairment.

Where to buy eszopiclone online:

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Here is a list of popular medications containing eszopiclone as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

Trade name of the drug	Pharmaceutical forms and doses	Companies
Fulnite	Tablets; Oral; 1 mg, 2 mg	Sun Pharmaceutical Industries
Hypnite	Tablets, Film-Coated; Oral; 1 mg, 2 mg, 3 mg	Consern Pharma
JustSleep	Tablets; Oral; 2 mg	Emcure Pharmaceuticals
Lunesta	Tablets; Oral; 1 mg, 2 mg, 3 mg	Sepracor Pharmaceuticals Eisai Sunovion Pharmaceuticals Waylis Therapeutics
Lunivia	Tablets; Oral; 2 mg, 3 mg	Sepracor Pharmaceuticals GlaxoSmithKline
Novo Insomnium	Tablets, Film-Coated; Oral; 2 mg, 3 mg	Gador
Sleepez	Tablets, Film-Coated; Oral; 1 mg, 2 mg, 3 mg	ChemiPharm
Valnoc	Tablets, Film-Coated; Oral; 2 mg, 3 mg	Drugtech Laboratorio Farmindustria Recalcine Laboratorios Synthesis Laboratorios
Zopimin	Tablets; Oral; 1 mg, 2 mg	Psyco Remedies
Zunestar	Tablets; Oral; 2 mg, 3 mg	Hab Pharmaceuticals & Research

Resource Links

Reliability and Validity for Life Care Planners - Why are we, as clinical practitioners, interested in research aimed at validating the process of life care planning?

Reading and Interpreting Life Care Planning Literature - The professional should be prepared to critically evaluate a study reported in the literature and apply that new knowledge to their professional practice and future investigative endeavors.

Ethics in Research - As practitioners and researchers, we have a responsibility to protect the research subject from potential harms . . .

Introduction to Evidence-based Practice - The practice of evidence-based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research.

Locating Practice Guidelines - When seeking clinical practice guidelines specific to the patient with whom you are working, you may begin your search in the following ways:

Sources of Research Information - There are numerous resources available to life care planners, but professionas need to know where information exists . . .